Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis

The paralogous Brr6 and Brl1 are conserved integral membrane proteins of the nuclear envelope (NE) with an unclear role in nuclear pore complex (NPC) biogenesis. Here, we analyzed double-degron mutants of Brr6/Brl1 to understand this function. Depletion of Brr6 and Brl1 caused defects in NPC biogene...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Zhang, Wanlu, Neuner, Annett, Rüthnick, Diana, Sachsenheimer, Timo, Lüchtenborg, Christian, Brügger, Britta, Schiebel, Elmar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839787/
https://ncbi.nlm.nih.gov/pubmed/29439116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706024
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