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Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis
The paralogous Brr6 and Brl1 are conserved integral membrane proteins of the nuclear envelope (NE) with an unclear role in nuclear pore complex (NPC) biogenesis. Here, we analyzed double-degron mutants of Brr6/Brl1 to understand this function. Depletion of Brr6 and Brl1 caused defects in NPC biogene...
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| Publicado en: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Rockefeller University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839787/ https://ncbi.nlm.nih.gov/pubmed/29439116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706024 |
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