Defusing inflammasomes

In this issue of JEM, Boucher et al. (https://doi.org/10.1084/jem.20172222) report isolation of active caspase-1 from macrophages after inflammasome activation. Surprisingly, they find that caspase-1 is quickly inactivated upon autoproteolytic processing.

Saved in:
Bibliographic Details
Published in:J Exp Med
Main Authors: Sandstrom, Andrew, Vance, Russell E.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2018
Subjects:
News
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839772/
https://ncbi.nlm.nih.gov/pubmed/29440361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180241
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items