Llwytho...
Initiation of inflammatory tumorigenesis by CTLA4 insufficiency due to type 2 cytokines
Genetically predisposed CTLA4 insufficiency in humans is associated with gastric cancer development, which is paradoxical to the prototypical role of CTLA4 in suppressing antitumor immunity. CTLA4 is a critical immune checkpoint against autoimmune disorders. Autoimmunity has been implicated in protu...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | J Exp Med |
|---|---|
| Prif Awduron: | , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Rockefeller University Press
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839767/ https://ncbi.nlm.nih.gov/pubmed/29374027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171971 |
| Tagiau: |
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