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Cross-differentiation from the CD8 lineage to CD4 T cells in the gut-associated microenvironment with a nonessential role of microbiota
CD4 and CD8 T-cell lineages differentiate through respective thymic selection processes. Here we report cross-differentiation from the CD8 lineage to CD4 T cells, but not vice versa, predominantly in the large-intestine-associated microenvironment. It occurred in the absence or distal presence of co...
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| Pubblicato in: | Cell Rep |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4383668/ https://ncbi.nlm.nih.gov/pubmed/25640181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.12.053 |
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