Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity

Depletion of immunosuppressive tumor-associated macrophages (TAMs) or reprogramming toward a proinflammatory activation state represent different strategies to therapeutically target this abundant myeloid population. In this study, we report that inhibition of colony-stimulating factor-1 receptor (C...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Hoves, Sabine, Ooi, Chia-Huey, Wolter, Carsten, Sade, Hadassah, Bissinger, Stefan, Schmittnaegel, Martina, Ast, Oliver, Giusti, Anna M., Wartha, Katharina, Runza, Valeria, Xu, Wei, Kienast, Yvonne, Cannarile, Michael A., Levitsky, Hyam, Romagnoli, Solange, De Palma, Michele, Rüttinger, Dominik, Ries, Carola H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839760/
https://ncbi.nlm.nih.gov/pubmed/29436396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171440
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