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Stac3 enhances expression of human Ca(V)1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels

Mutations of Ca(V)1.1, the pore-forming subunit of the L-type Ca(2+) channel in skeletal muscle, are an established cause of hypokalemic periodic paralysis (HypoPP). However, functional assessment of HypoPP mutant channels has been hampered by difficulties in achieving sufficient plasma membrane exp...

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Publicado en:J Gen Physiol
Autores principales: Wu, Fenfen, Quinonez, Marbella, DiFranco, Marino, Cannon, Stephen C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Rockefeller University Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839724/
https://ncbi.nlm.nih.gov/pubmed/29386226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711962
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