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Stac3 enhances expression of human Ca(V)1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels

Mutations of Ca(V)1.1, the pore-forming subunit of the L-type Ca(2+) channel in skeletal muscle, are an established cause of hypokalemic periodic paralysis (HypoPP). However, functional assessment of HypoPP mutant channels has been hampered by difficulties in achieving sufficient plasma membrane exp...

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Foilsithe in:J Gen Physiol
Main Authors: Wu, Fenfen, Quinonez, Marbella, DiFranco, Marino, Cannon, Stephen C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Rockefeller University Press 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839724/
https://ncbi.nlm.nih.gov/pubmed/29386226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711962
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