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Synergistic interplay between the two major bone minerals, hydroxyapatite and whitlockite nanoparticles, for osteogenic differentiation of mesenchymal stem cells

The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca(10)(PO(4))(6)(OH)(2)) and whitlockite (WH: Ca(18)Mg(2)(HPO(4))(2)(PO(4))(12)) minerals, where the WH phase occupies up to 20-35% of total weight. These two bone minerals have different crystal structures and physicochemic...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Cheng, Hao, Chabok, Rosa, Guan, Xiaofei, Chawla, Aditya, Li, Yuxiao, Khademhosseini, Ali, Jang, Hae Lin
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839653/
https://ncbi.nlm.nih.gov/pubmed/29366976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.01.016
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