Synergistic interplay between the two major bone minerals, hydroxyapatite and whitlockite nanoparticles, for osteogenic differentiation of mesenchymal stem cells

The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca(10)(PO(4))(6)(OH)(2)) and whitlockite (WH: Ca(18)Mg(2)(HPO(4))(2)(PO(4))(12)) minerals, where the WH phase occupies up to 20-35% of total weight. These two bone minerals have different crystal structures and physicochemic...

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Pubblicato in:Acta Biomater
Autori principali: Cheng, Hao, Chabok, Rosa, Guan, Xiaofei, Chawla, Aditya, Li, Yuxiao, Khademhosseini, Ali, Jang, Hae Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839653/
https://ncbi.nlm.nih.gov/pubmed/29366976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.01.016
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