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Synergistic interplay between the two major bone minerals, hydroxyapatite and whitlockite nanoparticles, for osteogenic differentiation of mesenchymal stem cells

The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca(10)(PO(4))(6)(OH)(2)) and whitlockite (WH: Ca(18)Mg(2)(HPO(4))(2)(PO(4))(12)) minerals, where the WH phase occupies up to 20-35% of total weight. These two bone minerals have different crystal structures and physicochemic...

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Détails bibliographiques
Publié dans:Acta Biomater
Auteurs principaux: Cheng, Hao, Chabok, Rosa, Guan, Xiaofei, Chawla, Aditya, Li, Yuxiao, Khademhosseini, Ali, Jang, Hae Lin
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839653/
https://ncbi.nlm.nih.gov/pubmed/29366976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.01.016
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