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Synergistic interplay between the two major bone minerals, hydroxyapatite and whitlockite nanoparticles, for osteogenic differentiation of mesenchymal stem cells

The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca(10)(PO(4))(6)(OH)(2)) and whitlockite (WH: Ca(18)Mg(2)(HPO(4))(2)(PO(4))(12)) minerals, where the WH phase occupies up to 20-35% of total weight. These two bone minerals have different crystal structures and physicochemic...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Biomater
Hauptverfasser: Cheng, Hao, Chabok, Rosa, Guan, Xiaofei, Chawla, Aditya, Li, Yuxiao, Khademhosseini, Ali, Jang, Hae Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839653/
https://ncbi.nlm.nih.gov/pubmed/29366976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.01.016
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