Synergistic interplay between the two major bone minerals, hydroxyapatite and whitlockite nanoparticles, for osteogenic differentiation of mesenchymal stem cells

The inorganic part of human bone is mainly composed of hydroxyapatite (HAP: Ca(10)(PO(4))(6)(OH)(2)) and whitlockite (WH: Ca(18)Mg(2)(HPO(4))(2)(PO(4))(12)) minerals, where the WH phase occupies up to 20-35% of total weight. These two bone minerals have different crystal structures and physicochemic...

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Bibliografiske detaljer
Udgivet i:Acta Biomater
Main Authors: Cheng, Hao, Chabok, Rosa, Guan, Xiaofei, Chawla, Aditya, Li, Yuxiao, Khademhosseini, Ali, Jang, Hae Lin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839653/
https://ncbi.nlm.nih.gov/pubmed/29366976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.01.016
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