A Mitochondrial Biomarker-Based Study of S-Equol in Alzheimer’s Disease Subjects: Results of a Single-Arm, Pilot Trial

Reductions in bioenergetic fluxes, mitochondrial enzyme activities, and mitochondrial number are observed in Alzheimer’s disease (AD). Preclinical work indicates estrogen pathway signaling by either estrogen or selective β estrogen receptor (ERβ) agonists benefits these parameters. To assess whether...

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Udgivet i:J Alzheimers Dis
Main Authors: Wilkins, Heather M., Mahnken, Jonathan D., Welch, Paul, Bothwell, Rebecca, Koppel, Scott, Jackson, Richard L., Burns, Jeffrey M., Swerdlow, Russell H.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839475/
https://ncbi.nlm.nih.gov/pubmed/28598847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-170077
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