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Effect of a Histone Deacetylases Inhibitor of IL-18 and TNF-Alpha Secretion in Vitro

BACKGROUND: Interleukin-18 (IL-18) and Tumor Necrosis Factor-alpha (TNF-α) are proinflammatory cytokines that increased the development of Th1 immune response, but have a different type of regulation of the gene expression. Whereas TNF-α has an inducible expression, IL-18 is translated as an inactiv...

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Detalhes bibliográficos
Publicado no:Open Access Maced J Med Sci
Main Authors: Dobreva, Zlatka Georgieva, Grigorov, Boncho Grigorov, Stanilova, Spaska Angelova
Formato: Artigo
Idioma:Inglês
Publicado em: Republic of Macedonia 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839430/
https://ncbi.nlm.nih.gov/pubmed/29531586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3889/oamjms.2018.075
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