CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer

Ovarian cancer (OC) has the highest rate of mortality among gynecological malignancy. Chemokine receptor CXCR2 in OC is associated with poor outcomes. However, the mechanisms by which CXCR2 regulates OC proliferation remain poorly understood. We generated CXCR2-positive cells from parental p53 wild-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Ignacio, Rosa Mistica C., Dong, Yuan-Lin, Kabir, Syeda M., Choi, Hyeongjwa, Lee, Eun-Sook, Wilson, Andrew J., Beeghly-Fadiel, Alicia, Whalen, Margaret M., Son, Deok-Soo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839399/
https://ncbi.nlm.nih.gov/pubmed/29515768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24231
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