Cell banking for regulatory T cell-based therapy: strategies to overcome the impact of cryopreservation on the Treg viability and phenotype

The first clinical trials with adoptive Treg therapy have shown safety and potential efficacy. Feasibility of such therapy could be improved if cells are cryopreserved and stored until optimal timing for infusion. Herein, we report the evaluation of two cell-banking strategies for Treg therapy: 1) c...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Gołąb, Karolina, Grose, Randall, Placencia, Veronica, Wickrema, Amittha, Solomina, Julia, Tibudan, Martin, Konsur, Evelyn, Ciepły, Kamil, Marek-Trzonkowska, Natalia, Trzonkowski, Piotr, Millis, J. Michael, Fung, John, Witkowski, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839397/
https://ncbi.nlm.nih.gov/pubmed/29515766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23887
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