Improved Coating of Pancreatic Islets with Regulatory T cells (Tregs) to Create Local Immunosuppression by Using Biotin-Polyethylene glycol-Succinimidyl Valeric Acid Ester Molecule

BACKGROUND: We showed that T regulatory (Treg) cells can be attached to the surface of pancreatic islets providing local immunoprotection. Further optimization of the method can improve coating efficiency, which may prolong graft survival. In this study, we compared the effectiveness of two differen...

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Detalhes bibliográficos
Publicado no:Transplant Proc
Main Authors: Gołąb, Karolina, Kizilel, Seda, Bal, Tugba, Hara, Manami, Zielinski, Mark, Grose, Randall, Savari, Omid, Wang, Xiao-Jun, Wang, Ling-Jia, Tibudan, Martin, Krzystyniak, Adam, Marek-Trzonkowska, Natalia, Millis, J Michael, Trzonkowski, Piotr, Witkowski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435942/
https://ncbi.nlm.nih.gov/pubmed/25131084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2014.05.075
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