TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer

Renal cell carcinoma (RCC) is a high-risk metastasizing tumor with a poor prognosis and poorly understood mechanism. In this study, we demonstrate that transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelia...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Meyer, Rosana D., Zou, Xueqing, Ali, Marwa, Ersoy, Esma, Bondzie, Philip Apraku, Lavaei, Mehrdad, Alexandrov, Ilya, Henderson, Joel, Rahimi, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839393/
https://ncbi.nlm.nih.gov/pubmed/29515762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23822
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