Recurrent extraneural sonic hedgehog medulloblastoma exhibiting sustained response to vismodegib and temozolomide monotherapies and inter-metastatic molecular heterogeneity at progression

BACKGROUND: Response to targeting and non-targeting agents is variable and molecular information remains poorly described in patients with recurrent sonic-hedgehog-driven medulloblastoma (SHH-MB). MATERIALS AND METHODS: Clinical and PET/CT findings during treatment with successive hedgehog antagonis...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Petrirena, Gregorio J., Masliah-Planchon, Julien, Sala, Quentin, Pourroy, Bertrand, Frappaz, Didier, Tabouret, Emeline, Graillon, Thomas, Gentet, Jean-Claude, Delattre, Olivier, Chinot, Olivier, Padovani, Laetitia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839382/
https://ncbi.nlm.nih.gov/pubmed/29515801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23699
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