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A Robust Optomotor Assay for Assessing the Efficacy of Optogenetic Tools for Vision Restoration
PURPOSE: To develop an animal behavioral assay for the quantitative assessment of the functional efficacy of optogenetic therapies. METHODS: A triple-knockout (TKO) mouse line, Gnat1(−/−)Cnga3(−/−)Opn4(−/−), and a double-knockout mouse line, Gnat1(−/−)Cnga3(−/−), were employed. The expression of cha...
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| Veröffentlicht in: | Invest Ophthalmol Vis Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Association for Research in Vision and Ophthalmology
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839255/ https://ncbi.nlm.nih.gov/pubmed/29625451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23278 |
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