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Petri net-based prediction of therapeutic targets that recover abnormally phosphorylated proteins in muscle atrophy

BACKGROUND: Muscle atrophy, an involuntary loss of muscle mass, is involved in various diseases and sometimes leads to mortality. However, therapeutics for muscle atrophy thus far have had limited effects. Here, we present a new approach for therapeutic target prediction using Petri net simulation o...

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Pubblicato in:BMC Syst Biol
Autori principali: Jung, Jinmyung, Kwon, Mijin, Bae, Sunghwa, Yim, Soorin, Lee, Doheon
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838966/
https://ncbi.nlm.nih.gov/pubmed/29506508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0555-0
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