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HIDEEP: a systems approach to predict hormone impacts on drug efficacy based on effect paths

Experimental evidence has shown that some of the human endogenous hormones significantly affect drug efficacy. Since hormone status varies with individual physiological states, it is essential to understand the interplay of hormones and drugs for precision medicine. Here, we developed an in silico m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kwon, Mijin, Jung, Jinmyung, Yu, Hasun, Lee, Doheon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709390/
https://ncbi.nlm.nih.gov/pubmed/29192270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16855-8
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