Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death

Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoevatromonoside (GEV) out of 46 CGs for its low nanom...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Schneider, Naira F. Z., Cerella, Claudia, Lee, Jin-Young, Mazumder, Aloran, Kim, Kyung Rok, de Carvalho, Annelise, Munkert, Jennifer, Pádua, Rodrigo M., Kreis, Wolfgang, Kim, Kyu-Won, Christov, Christo, Dicato, Mario, Kim, Hyun-Jung, Han, Byung Woo, Braga, Fernão C., Simões, Cláudia M. O., Diederich, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838923/
https://ncbi.nlm.nih.gov/pubmed/29545747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00070
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