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Changes in global translation elongation or initiation rates shape the proteome via the Kozak sequence

The sequence context surrounding the AUG start codon of an open reading frame - the ‘Kozak sequence’ - affects the probability with which a scanning ribosome will recognize the start codon and start translating there. A significant number of transcripts in animals such as Drosophila contain weak Koz...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Acevedo, Julieta M., Hoermann, Bernhard, Schlimbach, Tilo, Teleman, Aurelio A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838203/
https://ncbi.nlm.nih.gov/pubmed/29507361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22330-9
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