Microhomology-assisted scarless genome editing in human iPSCs

Gene-edited induced pluripotent stem cells (iPSCs) provide relevant isogenic human disease models in patient-specific or healthy genetic backgrounds. Towards this end, gene targeting using antibiotic selection along with engineered point mutations remains a reliable method to enrich edited cells. Ne...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Kim, Shin-Il, Matsumoto, Tomoko, Kagawa, Harunobu, Nakamura, Michiko, Hirohata, Ryoko, Ueno, Ayano, Ohishi, Maki, Sakuma, Tetsushi, Soga, Tomoyoshi, Yamamoto, Takashi, Woltjen, Knut
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838097/
https://ncbi.nlm.nih.gov/pubmed/29507284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03044-y
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki