A carregar...
Cyclic peptide inhibitors of lysine-specific demethylase 1 with improved potency identified by alanine scanning mutagenesis
Lysine-specific demethylase 1 (LSD1) is a chromatin-remodeling enzyme that plays an important role in cancer. Over-expression of LSD1 decreases methylation at histone 3 lysine 4, and aberrantly silences tumor suppressor genes. Inhibitors of LSD1 have been designed as chemical probes and potential an...
Na minha lista:
| Publicado no: | Eur J Med Chem |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837957/ https://ncbi.nlm.nih.gov/pubmed/29459279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.01.098 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|