Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults

BACKGROUND: Cross-sectional genome-wide association studies have identified hundreds of loci associated with blood lipids and related cardiovascular traits, but few genetic association studies have focused on long-term changes in blood lipids. METHODS: Participants from the GLACIER Study (N(max) = 3...

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Vydáno v:Int J Epidemiol
Hlavní autoři: Varga, Tibor V, Kurbasic, Azra, Aine, Mattias, Eriksson, Pontus, Ali, Ashfaq, Hindy, George, Gustafsson, Stefan, Luan, Jian’an, Shungin, Dmitry, Chen, Yan, Schulz, Christina-Alexandra, Nilsson, Peter M, Hallmans, Göran, Barroso, Inês, Deloukas, Panos, Langenberg, Claudia, Scott, Robert A, Wareham, Nicholas J, Lind, Lars, Ingelsson, Erik, Melander, Olle, Orho-Melander, Marju, Renström, Frida, Franks, Paul W
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Cardiovascular Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837581/
https://ncbi.nlm.nih.gov/pubmed/27864399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyw245
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