Evidence for large-scale gene-by-smoking interaction effects on pulmonary function

Background: Smoking is the strongest environmental risk factor for reduced pulmonary function. The genetic component of various pulmonary traits has also been demonstrated, and at least 26 loci have been reproducibly associated with either FEV(1) (forced expiratory volume in 1 second) or FEV(1)/FVC...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Int J Epidemiol
المؤلفون الرئيسيون: Aschard, Hugues, Tobin, Martin D, Hancock, Dana B, Skurnik, David, Sood, Akshay, James, Alan, Vernon Smith, Albert, Manichaikul, Ani W, Campbell, Archie, Prins, Bram P, Hayward, Caroline, Loth, Daan W, Porteous, David J, Strachan, David P, Zeggini, Eleftheria, O’Connor, George T, Brusselle, Guy G, Boezen, H Marike, Schulz, Holger, Deary, Ian J, Hall, Ian P, Rudan, Igor, Kaprio, Jaakko, Wilson, James F, Wilk, Jemma B, Huffman, Jennifer E, Hua Zhao, Jing, de Jong, Kim, Lyytikäinen, Leo-Pekka, Wain, Louise V, Jarvelin, Marjo-Riitta, Kähönen, Mika, Fornage, Myriam, Polasek, Ozren, Cassano, Patricia A, Barr, R Graham, Rawal, Rajesh, Harris, Sarah E, Gharib, Sina A, Enroth, Stefan, Heckbert, Susan R, Lehtimäki, Terho, Gyllensten, Ulf, Jackson, Victoria E, Gudnason, Vilmundur, Tang, Wenbo, Dupuis, Josée, Soler Artigas, María, Joshi, Amit D, London, Stephanie J, Kraft, Peter
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2017
الموضوعات:
Tobacco
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837518/
https://ncbi.nlm.nih.gov/pubmed/28082375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyw318
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