Predictive value of telomere length on outcome following acute myocardial infarction: evidence for contrasting effects of vascular vs. blood oxidative stress

AIMS: Experimental evidence suggests that telomere length (TL) is shortened by oxidative DNA damage, reflecting biological aging. We explore the value of blood (BTL) and vascular TL (VTL) as biomarkers of systemic/vascular oxidative stress in humans and test the clinical predictive value of BTL in a...

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Bibliografski detalji
Izdano u:Eur Heart J
Glavni autori: Margaritis, Marios, Sanna, Fabio, Lazaros, George, Akoumianakis, Ioannis, Patel, Sheena, Antonopoulos, Alexios S., Duke, Chloe, Herdman, Laura, Psarros, Costas, Oikonomou, Evangelos K., Shirodaria, Cheerag, Petrou, Mario, Sayeed, Rana, Krasopoulos, George, Lee, Regent, Tousoulis, Dimitris, Channon, Keith M., Antoniades, Charalambos
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Clinical Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837455/
https://ncbi.nlm.nih.gov/pubmed/28444175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehx177
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