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Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: the Standard care vs. Celecoxib Outcome Trial (SCOT)

BACKGROUND: Selective cyclooxygenase-2 inhibitors and conventional non-selective non-steroidal anti-inflammatory drugs (nsNSAIDs) have been associated with adverse cardiovascular (CV) effects. We compared the CV safety of switching to celecoxib vs. continuing nsNSAID therapy in a European setting. M...

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Publicat a:Eur Heart J
Autors principals: MacDonald, Thomas M., Hawkey, Chris J., Ford, Ian, McMurray, John J.V., Scheiman, James M., Hallas, Jesper, Findlay, Evelyn, Grobbee, Diederick E., Hobbs, F.D. Richard, Ralston, Stuart H., Reid, David M., Walters, Matthew R., Webster, John, Ruschitzka, Frank, Ritchie, Lewis D., Perez-Gutthann, Susana, Connolly, Eugene, Greenlaw, Nicola, Wilson, Adam, Wei, Li, Mackenzie, Isla S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837371/
https://ncbi.nlm.nih.gov/pubmed/27705888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw387
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