Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia

INTRODUCTION: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. The long-term management of gout requires reduction of serum urate levels and this is most often achieved with use of xanthine oxidase inhibitors, such as allopurinol. Febuxos...

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Główni autorzy: MacDonald, Thomas M, Ford, Ian, Nuki, George, Mackenzie, Isla S, De Caterina, Raffaele, Findlay, Evelyn, Hallas, Jesper, Hawkey, Christopher J, Ralston, Stuart, Walters, Matthew, Webster, John, McMurray, John, Perez Ruiz, Fernando, Jennings, Claudine G
Format: Artigo
Język:Inglês
Wydane: BMJ Publishing Group 2014
Hasła przedmiotowe:
Research Methods
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120410/
https://ncbi.nlm.nih.gov/pubmed/25011991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-005354
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