Protocol of the Febuxostat versus Allopurinol Streamlined Trial (FAST): a large prospective, randomised, open, blinded endpoint study comparing the cardiovascular safety of allopurinol and febuxostat in the management of symptomatic hyperuricaemia

INTRODUCTION: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. The long-term management of gout requires reduction of serum urate levels and this is most often achieved with use of xanthine oxidase inhibitors, such as allopurinol. Febuxos...

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Main Authors: MacDonald, Thomas M, Ford, Ian, Nuki, George, Mackenzie, Isla S, De Caterina, Raffaele, Findlay, Evelyn, Hallas, Jesper, Hawkey, Christopher J, Ralston, Stuart, Walters, Matthew, Webster, John, McMurray, John, Perez Ruiz, Fernando, Jennings, Claudine G
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2014
主題:
Research Methods
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120410/
https://ncbi.nlm.nih.gov/pubmed/25011991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-005354
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