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Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance
One of the goals of the Critical Path Institute’s Predictive Safety Testing Consortium (PSTC) is to promote best practices for evaluating novel markers of drug induced injury. This includes the use of sound statistical methods. For rat studies, these practices have centered around comparing the area...
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| Опубликовано в: : | Toxicol Sci |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5837334/ https://ncbi.nlm.nih.gov/pubmed/27815493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw225 |
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