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Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers

Appropriate quantification of added usefulness offered by new markers included in risk prediction algorithms is a problem of active research and debate. Standard methods, including statistical significance and c statistic are useful but not sufficient. Net reclassification improvement (NRI) offers a...

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Detalhes bibliográficos
Main Authors: Pencina, Michael J., Steyerberg, Ewout W., D’Agostino, Ralph B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341973/
https://ncbi.nlm.nih.gov/pubmed/21204120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.4085
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