A common missense variant of LILRB5 is associated with statin intolerance and myalgia

AIMS: A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) levels. Both biomarkers are released from injured muscle tissue, making t...

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Publicado en:Eur Heart J
Autores principales: K Siddiqui, Moneeza, Maroteau, Cyrielle, Veluchamy, Abirami, Tornio, Aleksi, Tavendale, Roger, Carr, Fiona, Abelega, Ngu-Uma, Carr, Dan, Bloch, Katyrzyna, Hallberg, Par, Yue, Qun-Ying, Pearson, Ewan R, Colhoun, Helen M, Morris, Andrew D, Dow, Eleanor, George, Jacob, Pirmohamed, Munir, Ridker, Paul M, Doney, Alex S F, Alfirevic, Ana, Wadelius, Mia, Maitland-van der Zee, Anke-Hilse, Chasman, Daniel I, Palmer, Colin N A
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
Materias:
Clinical Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837247/
https://ncbi.nlm.nih.gov/pubmed/29020356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehx467
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