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Targeting oncogenic Myc as a strategy for cancer treatment

The MYC family oncogene is deregulated in >50% of human cancers, and this deregulation is frequently associated with poor prognosis and unfavorable patient survival. Myc has a central role in almost every aspect of the oncogenic process, orchestrating proliferation, apoptosis, differentiation, an...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Chen, Hui, Liu, Hudan, Qing, Guoliang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837124/
https://ncbi.nlm.nih.gov/pubmed/29527331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-018-0008-7
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