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Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation
Homeobox (HOX) genes are frequently dysregulated in leukemia. Previous studies have shown that aberrant HOX gene expression accompanies leukemogenesis and affects disease progression and leukemia patient survival. Patients with acute myeloid leukemia (AML) bearing PML-RARα fusion gene have distinct...
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| Publicado no: | Epigenetics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5836981/ https://ncbi.nlm.nih.gov/pubmed/29224413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1413517 |
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