Ursodeoxycholic acid: Effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients

BACKGROUND & AIMS: Ursodeoxycholic acid (UDCA) is a secondary hydrophilic bile acid (BA) used as therapy for a range of hepatobiliary diseases. Its efficacy in non‐alcoholic fatty liver disease (NAFLD) is still under debate. Here, we aimed to decipher molecular mechanisms of UDCA in regulating e...

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Bibliografiske detaljer
Udgivet i:Liver Int
Main Authors: Mueller, Michaela, Castro, Rui E., Thorell, Anders, Marschall, Hanns‐Ulrich, Auer, Nicole, Herac, Merima, Rodrigues, Cecilia M.P., Trauner, Michael
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Genetic and Metabolic Liver Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836915/
https://ncbi.nlm.nih.gov/pubmed/28853202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13562
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