Exome sequencing of African-American prostate cancer reveals loss-of-function ERF mutations

African-American men have the highest incidence and mortality from prostate cancer. Whether a biological basis exists for this disparity remains unclear. Exome sequencing (n=102) and targeted validation (n = 90) of localized primary hormone-naïve prostate cancer in African-American men identified se...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Huang, Franklin W., Mosquera, Juan Miguel, Garofalo, Andrea, Oh, Coyin, Baco, Maria, Amin-Mansour, Ali, Rabasha, Bokang, Bahl, Samira, Mullane, Stephanie A., Robinson, Brian D., Aldubayan, Saud, Khani, Francesca, Karir, Beerinder, Kim, Eejung, Chimene-Weiss, Jeremy, Hofree, Matan, Romanel, Alessandro, Osborne, Joseph R., Kim, Jong Wook, Azabdaftari, Gissou, Woloszynska-Read, Anna, Sfanos, Karen, De Marzo, Angelo M., Demichelis, Francesca, Gabriel, Stacey, Van Allen, Eliezer M., Mesirov, Jill, Tamayo, Pablo, Rubin, Mark A., Powell, Isaac J., Garraway, Levi A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836784/
https://ncbi.nlm.nih.gov/pubmed/28515055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0960
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