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Luciferase activity of insect fatty acyl-CoA synthetases with synthetic luciferins

Long-chain fatty acyl-CoA synthetases (ACSLs) are homologs of firefly luciferase, but are incapable of emitting light with firefly luciferin. Recently, we found that an ACSL from the fruit fly Drosophila melanogaster is a latent luciferase that will emit light with the synthetic luciferin CycLuc2. H...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Mofford, David M., Liebmann, Kate L., Sankaran, Ganapathy Subramanian, Reddy, G.S. Kiran Kumar, Reddy, G. Randheer, Miller, Stephen C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836727/
https://ncbi.nlm.nih.gov/pubmed/29073357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00813
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