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Tacrolimus interacts with voriconazole to reduce the severity of fungal keratitis by suppressing IFN-related inflammatory responses and concomitant FK506 and voriconazole treatment suppresses fungal keratitis

PURPOSE: To investigate the expression and roles of type I and II interferons (IFNs) in fungal keratitis, as well as the therapeutic effects of tacrolimus (FK506) and voriconazole on this condition. METHODS: The mRNA and protein expression levels of type I (IFN-α/β) and II (IFN-γ) IFNs, as well as o...

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Publicat a:Mol Vis
Autors principals: Zhong, Jing, Peng, Lulu, Wang, Bowen, Zhang, Henan, Li, Saiqun, Yang, Ruhui, Deng, Yuqing, Huang, Haixiang, Yuan, Jin
Format: Artigo
Idioma:Inglês
Publicat: Molecular Vision 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836723/
https://ncbi.nlm.nih.gov/pubmed/29527115
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