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Tacrolimus (FK506) Suppresses TREM-1 Expression at an Early but Not at a Late Stage in a Murine Model of Fungal Keratitis
PURPOSE: To investigate the efficacy and mechanism of tacrolimus(FK506), which is a novel macrolide immunosuppressant, in inhibiting triggering receptor expressed on myeloid cells-1 (TREM-1) expression in a murine keratitis model induced by Aspergillus fumigatus. METHOD: TREM-1 was detected in 11 fu...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252117/ https://ncbi.nlm.nih.gov/pubmed/25464008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114386 |
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