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Coordination of FOXA2 and SIRT6 suppresses the hepatocellular carcinoma progression through ZEB2 inhibition

BACKGROUND: The Forkhead transcription family member FOXA2 plays a fundamental role in hepatocellular carcinoma (HCC) progression, but the precise interaction factor and molecular regulation of FOXA2 are not fully understood. OBJECTIVE: In this study, we found that FOXA2 could interact with sirtuin...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Liu, Jinghua, Yu, Zhen, Xiao, Yuanyuan, Meng, Qiong, Wang, Yeying, Chang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836661/
https://ncbi.nlm.nih.gov/pubmed/29535552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S150552
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