Inhibition of HMGB1 Suppresses Hepatocellular Carcinoma Progression via HIPK2-Mediated Autophagic Degradation of ZEB1

Autophagy is a conserved catabolic process maintaining cellular homeostasis and reportedly plays a critical role in tumor progression. Accumulating data show that autophagic activity is inhibited in hepatocellular carcinoma. However, the underlying molecular basis of impaired autophagy in HCC remain...

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Udgivet i:Front Oncol
Main Authors: Zhu, Wei, Li, Jun, Zhang, Yuheng, Zhu, Zhengyi, Liu, Hanyi, Lin, Yunzhen, Hu, Anyin, Zhou, Jingchao, Ren, Haozhen, Shi, Xiaolei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969871/
https://ncbi.nlm.nih.gov/pubmed/33747917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.599124
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