Differential Role of Cathepsins S and B In Hepatic APC-Mediated NKT Cell Activation and Cytokine Secretion

Natural killer T (NKT) cells exhibit a specific tissue distribution, displaying the liver the highest NKT/conventional T cell ratio. Upon antigen stimulation, NKT cells secrete Th1 cytokines, including interferon γ (IFNγ), and Th2 cytokines, including IL-4 that recruit and activate other innate immu...

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Vydáno v:Front Immunol
Hlavní autoři: de Mingo Pulido, Álvaro, de Gregorio, Estefanía, Chandra, Shilpi, Colell, Anna, Morales, Albert, Kronenberg, Mitchell, Marí, Montserrat
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836516/
https://ncbi.nlm.nih.gov/pubmed/29541077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00391
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