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Epidermal growth factor-mediated Rab25 pathway regulates integrin β1 trafficking in colon cancer

BACKGROUND: Integrins play a critical role in carcinogenesis. Integrin β1 localization is regulated by the guanosine-5′-triphosphate hydrolase Rab25 and integrin β1 levels are elevated in the serum of colon cancer patients; thus, the present study examined the effects of epidermal growth factor (EGF...

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Publicat a:Cancer Cell Int
Autors principals: Hong, Kyung Sook, Jeon, Eun-Young, Chung, Soon Sup, Kim, Kwang Ho, Lee, Ryung-Ah
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836438/
https://ncbi.nlm.nih.gov/pubmed/29515334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-018-0526-y
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