Loss of Rab25 promotes the development of skin squamous cell carcinoma through the dysregulation of integrin trafficking

Rab25 functions as either a tumor suppressor or tumor promoter across different tissues. Here we have demonstrated and clarified the role of Rab25 as a pivotal tumor suppressor of the skin squamous cell carcinoma (SCC) development. Rab25 loss was closely associated with the neoplastic transition in...

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Veröffentlicht in:J Pathol
Hauptverfasser: Jeong, Haengdueng, Lim, Kyung-Min, Kim, Kwang H., Cho, Yejin, Lee, Buhyun, Knowles, Byron C., Roland, Joseph T., Zwerner, Jeffrey P., Goldenring, James R., Nam, Ki Taek
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8075409/
https://ncbi.nlm.nih.gov/pubmed/31144312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5311
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