DNA methylation holds prognostic information in relapsed precursor B-cell acute lymphoblastic leukemia

BACKGROUND: Few biological markers are associated with survival after relapse of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In pediatric T-cell ALL, we have identified promoter-associated methylation alterations that correlate with prognosis. Here, the prognostic relevance of CpG islan...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Borssén, Magnus, Nordlund, Jessica, Haider, Zahra, Landfors, Mattias, Larsson, Pär, Kanerva, Jukka, Schmiegelow, Kjeld, Flaegstad, Trond, Jónsson, Ólafur Gísli, Frost, Britt-Marie, Palle, Josefine, Forestier, Erik, Heyman, Mats, Hultdin, Magnus, Lönnerholm, Gudmar, Degerman, Sofie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836434/
https://ncbi.nlm.nih.gov/pubmed/29515676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0466-3
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