DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia

BACKGROUND: We present a method that utilizes DNA methylation profiling for prediction of the cytogenetic subtypes of acute lymphoblastic leukemia (ALL) cells from pediatric ALL patients. The primary aim of our study was to improve risk stratification of ALL patients into treatment groups using DNA...

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Publicado en:Clin Epigenetics
Autores principales: Nordlund, Jessica, Bäcklin, Christofer L, Zachariadis, Vasilios, Cavelier, Lucia, Dahlberg, Johan, Öfverholm, Ingegerd, Barbany, Gisela, Nordgren, Ann, Övernäs, Elin, Abrahamsson, Jonas, Flaegstad, Trond, Heyman, Mats M, Jónsson, Ólafur G, Kanerva, Jukka, Larsson, Rolf, Palle, Josefine, Schmiegelow, Kjeld, Gustafsson, Mats G, Lönnerholm, Gudmar, Forestier, Erik, Syvänen, Ann-Christine
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343276/
https://ncbi.nlm.nih.gov/pubmed/25729447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-014-0039-z
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